By Joachim W. Fluhr, Peter Elsner, Enzo Berardesca, Howard I. Maibach
Bioengineering of the outside, or extra exactly the biophysical review of pores and skin body structure, is relocating speedily from a descriptive method of a deeper figuring out of biophysical and biochemical techniques. This moment variation of the preferred textual content Bioengineering of the outside: Water and Stratum Corneum displays the growth within the box, concentrating on the dramatically more suitable knowing of dermis body structure. particularly, it stories the shift in our realizing of the stratum corneum from an inert surrounding sheet to a biologically energetic compartment.
The stratum corneum is the interface among the occasionally harsh atmosphere and the inner turmoil of the human physique. in line with various fresh courses, this booklet explains the mechanisms serious about stratum corneum barrier functionality and hydration. It displays 10 years of development not just of the non-invasive biophysical review of epidermis body structure parameter, but additionally of the perfection of the to be had units. It brings all study on epidermal water and transepidermal water loss in future health and sickness updated with the revision of present chapters in addition to extra chapters from new participants on hydration and itching. This variation additionally contains new guidance at the standardization of measurements.
Bioengineering of the outside will increase communique in the learn group and should be necessary for scientists within the pores and skin bioengineering box by way of providing equipment that supply trustworthy and reproducible techniques for product trying out within the pharmaceutical and beauty industries, in addition to for uncomplicated examine
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Extra resources for Bioengineering of the Skin: Water and the Stratum Corneum, 2nd Edition
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Water molecules are mainly located in the amorphous part of keratin, between the microfibrils, which are moved away. Removing the hair cuticle by means of a razor blade, for example, results in a much more marked swelling, which demonstrates the role of the cuticle in strongly limiting the water sorption by the hair cortex. IX. CONCLUSION Water has considerable influence on the physical properties of both hair and the SC. For example, there is a coefficient of about 100 between the elasticity modules measured in dry and humid conditions , whereas electrical conductance is multiplied by a factor of 10,000 between dry and hydrated samples .
W. et al. Preparation of liposomes from stratum corneum lipids, J. Invest. , 87, 582, 1986. 69. , Effect of epidermal acylglucosylceramides and acylceramides on the morphology of liposomes prepared from stratum corneum lipids, Biochim. Biophys. Acta, 939, 403, 1988. 70. Abraham, W. et al. Stratum corneum lipid liposomes: calcium-induced transformation into lamellar sheets, J. Invest. , 88, 212, 1987. 71. , Structures formed by epidermal lipids in vitro, Semin. , 11, 121, 1992. 72. T. et al. Partition of sodium dodecyl sulfate into stratum corneum lipid liposomes, Arch.